Successful site selection in one connected workflow

Turn site, investigator, and patient insights into faster enrollment and stronger trial performance.

Select sites with confidence

Site Selection & Optimization brings together patient access, investigator performance, and enrollment intelligence to help teams build country and site strategies that recruit faster and improve trial performance.

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Find the right patients

See where eligible patients receive care and where recruitment opportunities are strongest.

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Find the right investigators

Rank investigators on experience, performance, capacity, and enrollment potential.

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Avoid recruitment risks

Identify competing trial activity, site capacity, and enrollment challenges before selection.

The Clinical Intelligence Platform

Site selection connected to the full clinical workflow​

Connect Clinical Competitive Intelligence with the workflows shaping trial design, site selection, and patient recruitment.
Citeline workflow diagram Five workflows around a central Citeline Data & APIs hub. CompetitiveIntelligence ProtocolOptimization SiteSelection Patient Strategy& Recruitment Regulatory& Disclosure CitelineData & APIs Patient Intelligence Agentic Workflows

Clinical Competitive Intelligence

Understand the competitive picture. Identify where to invest and where to compete.

Protocol Optimization & Trial Design

Design protocols real patients can qualify for, grounded in competitive evidence.

Site Selection & Optimization

Place trials where eligible patients and capable sites meet.

Patient Strategy and Recruitment

Reach the right patients at the right moment.

Regulatory & Disclosure

Stay compliant and meet critical reporting obligations.

Why it matters

Site selection decisions have big consequences

Selecting the wrong countries, sites, or investigators can slow enrollment, increase costs, and put timelines at risk.
11%
of sites ready to recruit enroll no patients
41%
of activated sites fall short of enrollment targets
53%
of trials extend their planned enrollment timelines
~$40K
average cost per extra day a Phase II or III trial runs
Sources: Tufts Center for the Study of Drug Development (Tufts CSDD), 2012 and 2024.
Site Selection in practice

What you can do with Site Selection

Build a stronger site strategy

Test eligibility criteria against real-world patient populations before the protocol is finalized.
  • See the impact of eligibility criteria on patient availability
  • Identify the strongest countries and sites for your study
  • Forecast enrollment based on your study criteria

Discover best-fit investigators

Identify investigators with the experience, capacity, and track record to deliver your study.

  • Search 500K+ investigators across 185 countries
  • Surface investigators beyond existing networks
  • Compare performance and capacity before selection

Reduce enrollment risk

Forecast recruitment performance before finalizing country, site, and investigator decisions.

  • Assess patient availability across target geographies
  • Forecast enrollment before sites are selected
  • Account for competing trials recruiting the same patients
Products & Data

Explore the products behind the workflow

Clinical intelligence, patient data, and AI-powered applications working together in one connected workflow.
Patient intelligence

Put patients at the center of site selection

Patient Intelligence, powered by NorstellaLinQ, helps teams understand where patients are, how they move through care, and which sites are best positioned to reach them, bringing patient access into site selection from the start.

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Patient availability

Understand where eligible patients receive care.

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Care pathways

See how patients move between providers and specialists.

Site opportunity

Identify sites with the strongest access to eligible patients.

Proof

Built on the industry's most robust site and investigator intelligence

Site Selection combines investigator performance data, patient access intelligence, and clinical trial benchmarks to help teams make better country and site decisions.

190K+
Sites worldwide
500K+
Investigators
185
Countries covered
60K+

Curated trials with reported enrollment results

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Analyst-curated intelligence

Built on curated clinical trial, site, and investigator intelligence maintained by Citeline analysts.

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Proprietary performance data

Benchmark sites and investigators using enrollment performance, activation timelines, and historical trial outcomes.

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Global site intelligence

Evaluate sites and investigators across 185 countries, including individual site performance and capacity.

How it compares

From relationship-led to evidence-led selection

Rank countries, sites, and investigators using patient access, performance data, and enrollment intelligence in one connected workflow.
Traditional Approach The Site Selection Workflow
Sites selected based on existing relationships Sites ranked by performance, capacity, and patient access
Historical averages used to estimate enrollment Enrollment potential forecast before selection
Limited visibility into competing studies Competing trial activity visible at site level
Patient access inferred from assumptions Patient density mapped around each site
Known investigators prioritized Investigators recommended based on protocol fit
Decisions spread across disconnected tools Countries, sites, and investigators evaluated in one workflow
Pricing

Speak with our team to learn how Site Selection & Optimization fits your study start-up process

latest resources

Go deeper on site selection

A female doctor in a white coat with a stethoscope sitting at a desk, while a female patient in an orange top sits across from her, holding her hands near her chest.
Article

Citeline’s Patient Recruitment Pulse – October 2026 Edition

Hand selecting a glowing digital profile card among multiple candidate resumes displayed above a laptop keyboard.
Customer Story

The Power of Partnership: Pivoting a Plus for Recruitment Project

Article

The Challenges of Recruiting for Pediatric Trials

FAQ

Frequently Asked Questions

Site Selection is designed for sponsors and CROs responsible for country strategy, site selection, feasibility, and enrollment planning.
Site Selection brings together Sitetrove+, Trialtrove+, Patient Intelligence, Investigator SmartSelect, and Cohort SmartBuilder.
Site Selection combines patient access, investigator performance, site intelligence, and competing trial activity before feasibility outreach begins.
Patient Intelligence helps teams understand where eligible patients receive care and incorporate patient access into country and site decisions.
Yes. Site Selection includes trial intelligence that can be used to evaluate competing studies and investigator workload.
Investigator recommendations are informed by therapeutic experience, study activity, performance history, capacity indicators, and protocol alignment.
Yes. Site, investigator, and organization data can be accessed through APIs and integrated into internal workflows and reporting environments.
Get started

Speak to the Site Selection team

Tell us where your study start-up sits today and we’ll show you the fastest path to a site list that enrolls.

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